Completed PHASE3 INTERVENTIONAL 3-arm NCT00575055

Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Carrier)

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Trial of Bapineuzumab (AAB-001, ELN115727) In Patients With Mild to Moderate Alzheimer's Disease Who Are Apolipoprotein E4 Carriers.

Sponsor: JANSSEN Alzheimer Immunotherapy Research & Development, LLC

Conditions Alzheimer's Disease

Interventions Bapineuzumab 0.5 mg/kg Bapineuzumab 1.0 m/kg Placebo Control

Updated 8 times since 2017 Last updated: Oct 30, 2013 Started: Dec 31, 2007 Primary completion: Apr 30, 2012 Completion: Apr 30, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Alzheimer's Disease and is currently completed. JANSSEN Alzheimer Immunotherapy Research & Development, LLC leads this study, which shows 8 recorded versions since 2007 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Apr 2022 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Apr 2022 [monthly]

Completed PHASE3

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Dec 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

JANSSEN Alzheimer Immunotherapy Research & Development, LLC
Pfizer

Data source: JANSSEN Alzheimer Immunotherapy Research & Development, LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Abington, United States , Albany, United States , Albuquerque, United States , Alexandria, United States , Allentown, United States , Ann Arbor, United States , Atlanta, United States , Atlantis, United States , Baltimore, United States , Beachwood, United States and 132 more locations