Terminated PHASE2 INTERVENTIONAL 1-arm NCT00589602

T-Cell Depletion, Donor Hematopoietic Stem Cell Transplant (HSCT), and T-Cell Infusions in Treating Patients With Hematologic Cancer or Other Diseases

Phase II Feasibility Study of T-Cell Depletion in Allogeneic Unrelated Bone Marrow Transplantation (MUD ALLO BMT) Followed by Delayed T-Cell Infusions

Sponsor: National Cancer Institute (NCI)

Conditions Chronic Myeloproliferative Disorders Leukemia Lymphoma Multiple Myeloma and Malignant Plasma Cell Neoplasms Myelodysplastic Syndromes Precancerous/Nonmalignant Condition Secondary Myelofibrosis

Interventions allogeneic hematopoietic stem cell transplantation peripheral blood lymphocyte therapy peripheral blood stem cell transplantation total-body irradiation (TBI)

Updated 7 times since 2017 Last updated: Apr 18, 2017 Started: Jan 31, 2004 Primary completion: Aug 31, 2009 Completion: Dec 31, 2014

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

slow accrual

Other terminated trials from National Cancer Institute (NCI)

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Other Chronic Myeloproliferative Disorders trials with similar outcome

Browse all Chronic Myeloproliferative Disorders trials

This PHASE2 trial investigates Chronic Myeloproliferative Disorders and Leukemia and is currently terminated or withdrawn. National Cancer Institute (NCI) leads this study, which shows 7 recorded versions since 2004 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Terminated PHASE2
Jul 2024 — Sep 2024 [monthly]

Terminated PHASE2
Jan 2021 — Jul 2024 [monthly]

Terminated PHASE2
Jun 2018 — Jan 2021 [monthly]

Terminated PHASE2
Jul 2017 — Jun 2018 [monthly]

Terminated PHASE2

Status: Unknown Status → Terminated

▶ Show 2 earlier versions

Feb 2017 — Jul 2017 [monthly]

Unknown Status PHASE2
Jan 2017 — Feb 2017 [monthly]

Unknown Status PHASE2

First recorded

Jan 2004

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Cancer Institute (NCI)
The Cleveland Clinic

Data source: The Cleveland Clinic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Cleveland, United States