Completed PHASE2 INTERVENTIONAL 4-arm NCT00600938

Evaluating Use of Deferasirox as Compared to Deferoxamine in Treating Cardiac Iron Overload (CORDELIA)

A Multicenter, Randomized, Open-label Phase II Trial Evaluating Deferasirox Compared With Deferoxamine in Patients With Cardiac Iron Overload Due to Chronic Blood Transfusions

Sponsor: Novartis Pharmaceuticals

Conditions Transfusional Hemosiderosis Transfusional Iron Overload

Interventions Core Study: Deferasirox Core Study: Deferoxamine Deferasirox Deferoxamine Extension: deferasirox to deferoxamine Extension: deferoxamine to deferasirox

Updated 7 times since 2017 Last updated: Aug 13, 2014 Started: Nov 30, 2007 Primary completion: Mar 31, 2013 Completion: Mar 31, 2013

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00600938, this PHASE2 trial focuses on Transfusional Hemosiderosis and Transfusional Iron Overload and remains completed. Sponsored by Novartis Pharmaceuticals, it has been updated 7 times since 2007, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Jan 2021 — Jul 2024 [monthly]

Completed PHASE2
Jun 2018 — Jan 2021 [monthly]

Completed PHASE2

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Nov 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Novartis Pharmaceuticals

Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adana, Turkey (Türkiye) , Al Mansurah, Egypt , Ankara, Turkey (Türkiye) , Antalya, Turkey (Türkiye) , Bangkok, Thailand , Cagliari, Italy , Cairo, Egypt , Dubai, United Arab Emirates , Genova, Italy , Hazmiyeh, Lebanon and 8 more locations