deltatrials
Completed PHASE2 INTERVENTIONAL 4-arm NCT00625846

Pazopanib Hydrochloride in Treating Patients With Advanced Thyroid Cancer

A Phase II Study of GW 786034 (Pazopanib) in Advanced Thyroid Cancer

Sponsor: National Cancer Institute (NCI)

Conditions Recurrent Thyroid Gland Carcinoma Stage III Differentiated Thyroid Gland Carcinoma AJCC v7 Stage III Thyroid Gland Medullary Carcinoma AJCC v7 Stage IVA Differentiated Thyroid Gland Carcinoma AJCC v7 Stage IVA Thyroid Gland Anaplastic Carcinoma AJCC v7 Stage IVA Thyroid Gland Medullary Carcinoma AJCC v7 Stage IVB Differentiated Thyroid Gland Carcinoma AJCC v7 Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v7 Stage IVB Thyroid Gland Medullary Carcinoma AJCC v7 Stage IVC Differentiated Thyroid Gland Carcinoma AJCC v7 Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v7 Stage IVC Thyroid Gland Medullary Carcinoma AJCC v7 Thyroid Gland Anaplastic Carcinoma
Interventions Laboratory Biomarker Analysis Pazopanib Hydrochloride
Updated 20 times since 2017 Last updated: Feb 4, 2020 Started: Feb 22, 2008 Primary completion: Dec 21, 2018 Completion: Aug 13, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Recurrent Thyroid Gland Carcinoma and Stage III Differentiated Thyroid Gland Carcinoma AJCC v7, this trial is completed. The trial is conducted by National Cancer Institute (NCI) and has accumulated 20 data snapshots since 2008. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Oct 2017 · 4 months · monthly snapshot~Oct 2017 – ~Feb 2018 · 4 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Jun 2019 · 6 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

20 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Mar 2020 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

▶ Show 15 earlier versions

  1. Feb 2020 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

  2. Jan 2020 — Feb 2020 [monthly]

    Active Not Recruiting PHASE2

  3. Dec 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE2

  4. Oct 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE2

  5. Sep 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE2

  6. Aug 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE2

  7. Jul 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE2

  8. Jun 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE2

  9. Dec 2018 — Jun 2019 [monthly]

    Active Not Recruiting PHASE2

  10. Jun 2018 — Dec 2018 [monthly]

    Active Not Recruiting PHASE2

  11. Feb 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  12. Oct 2017 — Feb 2018 [monthly]

    Active Not Recruiting PHASE2

  13. Jun 2017 — Oct 2017 [monthly]

    Active Not Recruiting PHASE2

  14. Feb 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE2

  15. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Feb 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aurora, United States , Baltimore, United States , Burnsville, United States , Detroit, United States , Edina, United States , Fridley, United States , Iowa City, United States , Jacksonville, United States , Madison, United States , Maplewood, United States and 10 more locations