Completed PHASE3 INTERVENTIONAL 2-arm NCT00633880

Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (NOH302)

Phase III, Multi-Center, Study to Assess the Clinical Effect of Droxidopa in Subjects With Primary Autonomic Failure, Dopamine Beta Hydroxylase Deficiency or Non-Diabetic Neuropathy and Symptomatic NOH

Sponsor: Chelsea Therapeutics

Conditions Dopamine Beta Hydroxylase Deficiency Non-diabetic Neuropathy Primary Autonomic Failure Symptomatic Neurogenic Orthostatic Hypotension (NOH)

Interventions Droxidopa Placebo

Updated 7 times since 2017 Last updated: Apr 22, 2014 Started: Jan 31, 2008 Primary completion: Aug 31, 2009 Completion: Sep 30, 2009

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Dopamine Beta Hydroxylase Deficiency and Non-diabetic Neuropathy, this trial is completed. The trial is conducted by Chelsea Therapeutics and has accumulated 7 data snapshots since 2008. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Jan 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Chelsea Therapeutics
Chiltern International Inc.

Data source: Chelsea Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adelaide, Australia , Baltimore, United States , Baytown, United States , Birmingham, United States , Boca Raton, United States , Boston, United States , Canton, United States , Chicago, United States , Christchurch, New Zealand , Cincinnati, United States and 41 more locations