Completed PHASE3 INTERVENTIONAL 2-arm NCT00640367

Intra-arterial Versus Systemic Thrombolysis for Acute Ischemic Stroke (SYNTHESIS EXP)

Synthesis Expansion: A Randomized Controlled Trial on Intra-Arterial Versus Intravenous Thrombolysis in Acute Ischemic Stroke

Sponsor: Niguarda Hospital

Conditions Cerebrovascular Accident Stroke

Interventions Alteplase IA and/or mechanical thrombolysis Alteplase IV

Updated 6 times since 2017 Last updated: Apr 24, 2014 Started: Feb 29, 2008 Primary completion: Feb 28, 2009 Completion: Jul 31, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00640367, this PHASE3 trial focuses on Cerebrovascular Accident and Stroke and remains completed. Sponsored by Niguarda Hospital, it has been updated 6 times since 2008, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

6 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3

▶ Show 1 earlier version

Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Feb 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Niguarda Hospital

Data source: Niguarda Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Milan, Italy