deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 5-arm NCT00655395

Treatment of Elderly Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic (MD) Syndrome With Laromustine and Infusional Cytarabine

A Phase I/Phase II Evaluation of Laromustine (VNP40101M), A Sulfonylhydrazine Alkylating Agent, Combined With Infusional Cytarabine in Elderly Patients With Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

Sponsor: Vion Pharmaceuticals

Updated 8 times since 2017 Last updated: Jan 25, 2019 Started: Mar 31, 2008 Primary completion: Apr 30, 2010 Completion: Oct 31, 2010
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This trial was terminated. No reason was provided.

This PHASE1/PHASE2 trial investigates Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) and is currently terminated or withdrawn. Vion Pharmaceuticals leads this study, which shows 8 recorded versions since 2008 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotUnknown Status~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotUnknown Status~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotUnknown Status~Sep 2018 – ~Feb 2019 · 5 months · monthly snapshotTerminated~Feb 2019 – ~Jan 2021 · 23 months · monthly snapshotTerminated~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 23 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

  4. Feb 2019 — Jan 2021 [monthly]

    Terminated PHASE1_PHASE2

  5. Sep 2018 — Feb 2019 [monthly]

    Terminated PHASE1_PHASE2

    Status: Unknown StatusTerminated

Show 3 earlier versions
  1. Jun 2018 — Sep 2018 [monthly]

    Unknown Status PHASE1_PHASE2

  2. Feb 2017 — Jun 2018 [monthly]

    Unknown Status PHASE1_PHASE2

  3. Jan 2017 — Feb 2017 [monthly]

    Unknown Status PHASE1_PHASE2

    First recorded

Mar 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Vion Pharmaceuticals
  • Viron Therapeutics Inc
Data source: Viron Therapeutics Inc

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations