deltatrials
Completed NCT00667121

Tamoxifen in Women With Breast Cancer and in Women at High-Risk of Breast Cancer Who Are Receiving Venlafaxine, Citalopram, Escitalopram, Gabapentin, or Sertraline

The Effect of Antidepressants and Gabapentin on Tamoxifen Pharmacokinetics: A Prospective Study

Sponsor: Mayo Clinic

Conditions Breast Cancer Depression Hot Flashes Psychosocial Effects of Cancer and Its Treatment
Interventions adjuvant therapy citalopram hydrobromide escitalopram oxalate gabapentin high performance liquid chromatography laboratory biomarker analysis molecular genetic technique pharmacological study sertraline hydrochloride tamoxifen citrate venlafaxine
Updated 17 times since 2017 Last updated: Feb 12, 2025 Started: Mar 16, 2011 Primary completion: May 12, 2014 Completion: May 27, 2014

Listed as NCT00667121, this observational or N/A phase trial focuses on Breast Cancer and Depression and remains completed. Sponsored by Mayo Clinic, it has been updated 17 times since 2011, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Change History

17 versions recorded

  1. Mar 2025 — Present [monthly]

    Completed

  2. Sep 2024 — Mar 2025 [monthly]

    Completed

    Status: Active Not Recruiting → Completed

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting

  4. Oct 2023 — Jul 2024 [monthly]

    Active Not Recruiting

  5. Feb 2023 — Oct 2023 [monthly]

    Active Not Recruiting

▶ Show 12 earlier versions

  1. Mar 2022 — Feb 2023 [monthly]

    Active Not Recruiting

  2. Nov 2021 — Mar 2022 [monthly]

    Active Not Recruiting

  3. Jan 2021 — Nov 2021 [monthly]

    Active Not Recruiting

  4. Oct 2020 — Jan 2021 [monthly]

    Active Not Recruiting

  5. Jan 2020 — Oct 2020 [monthly]

    Active Not Recruiting

  6. Mar 2019 — Jan 2020 [monthly]

    Active Not Recruiting

  7. Sep 2018 — Mar 2019 [monthly]

    Active Not Recruiting

  8. Jun 2018 — Sep 2018 [monthly]

    Active Not Recruiting

  9. Apr 2018 — Jun 2018 [monthly]

    Active Not Recruiting

    Phase: NA → None

  10. Sep 2017 — Apr 2018 [monthly]

    Active Not Recruiting NA

  11. Feb 2017 — Sep 2017 [monthly]

    Active Not Recruiting NA

  12. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting NA

    First recorded

Mar 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mayo Clinic
Data source: Mayo Clinic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

  • • Ann Arbor, United States
  • • Arlington, United States
  • • Baltimore, United States
  • • Chapel Hill, United States
  • • Indianapolis, United States
  • • Rochester, United States