deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT00667615

Trial of Vorinostat in Combination With Cyclophosphamide, Etoposide, Prednisone and Rituximab for Elderly Patients With Relapsed Diffuse Large B-Cell Lymphoma (DLBCL)

A Multi-Center Phase I/II Trial of Vorinostat in Combination With Cyclophosphamide, Etoposide, Prednisone and Rituximab for Elderly Patients With Relapsed Diffuse Large B-Cell Lymphoma (DLBCL)

Sponsor: Endeavor Health

Updated 14 times since 2017 Last updated: Dec 7, 2017 Started: Apr 30, 2008 Primary completion: Feb 28, 2017 Completion: Feb 28, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Hodgkin's Disease and Lymphoma, this trial is completed. The trial is conducted by Endeavor Health and has accumulated 14 data snapshots since 2008. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~Dec 2017 · 9 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Aug 2019 · 14 months · monthly snapshot~Aug 2019 – ~Jan 2021 · 17 months · monthly snapshot~Jan 2021 – ~Jun 2022 · 17 months · monthly snapshot~Jun 2022 – ~Dec 2022 · 6 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – present · 13 months · monthly snapshot~Jan 2026 – present · 3 months · monthly snapshot

Change History

14 versions recorded
  1. Jan 2026 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Mar 2025 — Present [monthly]

    Completed PHASE1/PHASE2

  3. Sep 2024 — Mar 2025 [monthly]

    Completed PHASE1/PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  5. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

Show 9 earlier versions
  1. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE1_PHASE2

  2. Jun 2022 — Dec 2022 [monthly]

    Completed PHASE1_PHASE2

  3. Jan 2021 — Jun 2022 [monthly]

    Completed PHASE1_PHASE2

  4. Aug 2019 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

  5. Jun 2018 — Aug 2019 [monthly]

    Completed PHASE1_PHASE2

  6. Dec 2017 — Jun 2018 [monthly]

    Completed PHASE1_PHASE2

  7. Mar 2017 — Dec 2017 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted

  8. Feb 2017 — Mar 2017 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  9. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    First recorded

Apr 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Endeavor Health
  • Memorial Sloan Kettering Cancer Center
  • Merck Sharp & Dohme LLC
  • Northwestern University
  • Weill Medical College of Cornell University
Data source: Memorial Sloan Kettering Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .