deltatrials
Completed OBSERVATIONAL NCT00677768

Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS) (BIO_ALS-01)

A Multicenter Study for the Validation of ALS Biomarkers

Sponsor: ALS Association

Interventions No intervention
Updated 11 times since 2017 Last updated: Jun 2, 2016 Started: Apr 30, 2008 Primary completion: Nov 30, 2015 Completion: Nov 30, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00677768, this observational or N/A phase trial focuses on Amyotrophic Lateral Sclerosis and Hereditary Spastic Paraparesis and remains completed. Sponsored by ALS Association, it has been updated 11 times since 2008, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshotCompleted~Aug 2017 – ~Apr 2018 · 8 months · monthly snapshotCompleted~Apr 2018 – ~May 2018 · 30 days · monthly snapshotCompleted~May 2018 – ~Jun 2018 · 31 days · monthly snapshotCompleted~Jun 2018 – ~Nov 2020 · 29 months · monthly snapshotCompleted~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotCompleted~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotCompleted~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 9 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed

  2. Sep 2024 — Sep 2025 [monthly]

    Completed

  3. Jul 2024 — Sep 2024 [monthly]

    Completed

  4. Dec 2021 — Jul 2024 [monthly]

    Completed

  5. Jan 2021 — Dec 2021 [monthly]

    Completed

Show 6 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Completed

  2. Jun 2018 — Nov 2020 [monthly]

    Completed

  3. May 2018 — Jun 2018 [monthly]

    Completed

  4. Apr 2018 — May 2018 [monthly]

    Completed

    Phase: NANone

  5. Aug 2017 — Apr 2018 [monthly]

    Completed NA

  6. Jan 2017 — Aug 2017 [monthly]

    Completed NA

    First recorded

Apr 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • ALS Association
  • ALS Therapy Alliance
  • Massachusetts General Hospital
  • National Institute of Neurological Disorders and Stroke (NINDS)
  • National Institutes of Health (NIH)
Data source: Massachusetts General Hospital

For direct contact, visit the study record on ClinicalTrials.gov .