deltatrials
Completed PHASE2 INTERVENTIONAL 4-arm NCT00679783

Phase II Study of AZD2281 in Patients With Known BRCA Mutation Status or Recurrent High Grade Ovarian Cancer or Patients With Known BRCA Mutation Status/ Triple Neg Breast Cancer

Phase II, Open Label, Non-Randomized Study of AZD2281 in the Treatment of Patients With Known BRCA or Recurrent High Grade Serous/ Undifferentiated Tubo-Ovarian Carcinoma and in Known BRCA or Triple Negative Breast Cancer to Determine Response Rate and Correlative Markers of Response

Sponsor: AstraZeneca

Conditions Breast Cancer Ovarian Carcinoma
Interventions AZD2281
Updated 24 times since 2017 Last updated: Jul 7, 2023 Started: Jul 8, 2008 Primary completion: Mar 26, 2010 Completion: Jul 20, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Breast Cancer and Ovarian Carcinoma, this trial is completed. The trial is conducted by AstraZeneca and has accumulated 24 data snapshots since 2008. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshot~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Oct 2018 · 3 months · monthly snapshot~Oct 2018 – ~Mar 2019 · 5 months · monthly snapshot~Mar 2019 – ~Jun 2019 · 3 months · monthly snapshot~Jun 2019 – ~Sep 2019 · 3 months · monthly snapshot~Sep 2019 – ~Jan 2020 · 4 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~Aug 2020 · 4 months · monthly snapshot~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Apr 2022 · 4 months · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Aug 2023 · 11 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 23 months · monthly snapshot

Change History

24 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Aug 2023 — Jul 2024 [monthly]

    Completed PHASE2

  4. Sep 2022 — Aug 2023 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  5. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2

▶ Show 19 earlier versions

  1. Apr 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE2

  2. Dec 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE2

  3. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE2

  4. Sep 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE2

  5. Apr 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  6. Jan 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE2

  7. Oct 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  8. Aug 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE2

  9. Apr 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

  10. Jan 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE2

  11. Sep 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE2

  12. Jun 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE2

  13. Mar 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE2

  14. Oct 2018 — Mar 2019 [monthly]

    Active Not Recruiting PHASE2

  15. Jul 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE2

  16. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE2

  17. Sep 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  18. Feb 2017 — Sep 2017 [monthly]

    Active Not Recruiting PHASE2

  19. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Jul 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • British Columbia Cancer Agency
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations