deltatrials
Terminated PHASE2 NCT00727194

Safety and Efficacy Study of Eculizumab in Patients With Refractory Generalized Myasthenia Gravis

A Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Multi-Center Study of Eculizumab in Patients With Generalized Myasthenia Gravis (gMG) Who Have Moderate to Severe Muscle Weakness Despite Treatment With Immunosuppressants

Sponsor: Alexion Pharmaceuticals, Inc.

Updated 14 times since 2017 Last updated: Sep 13, 2019 Started: Oct 31, 2008 Primary completion: Mar 31, 2011 Completion: Jul 31, 2011

This PHASE2 trial investigates Myasthenia Gravis and is currently terminated or withdrawn. Alexion Pharmaceuticals, Inc. leads this study, which shows 14 recorded versions since 2008 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshot~Aug 2017 – ~May 2018 · 9 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jun 2019 · 12 months · monthly snapshot~Jun 2019 – ~Oct 2019 · 4 months · monthly snapshot~Oct 2019 – ~Nov 2020 · 13 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Apr 2023 · 16 months · monthly snapshot~Apr 2023 – ~Dec 2023 · 8 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 19 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Dec 2023 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Apr 2023 — Dec 2023 [monthly]

    Terminated PHASE2

  5. Dec 2021 — Apr 2023 [monthly]

    Terminated PHASE2

Show 9 earlier versions
  1. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE2

  2. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  3. Oct 2019 — Nov 2020 [monthly]

    Terminated PHASE2

  4. Jun 2019 — Oct 2019 [monthly]

    Terminated PHASE2

  5. Jun 2018 — Jun 2019 [monthly]

    Terminated PHASE2

  6. May 2018 — Jun 2018 [monthly]

    Terminated PHASE2

  7. Aug 2017 — May 2018 [monthly]

    Terminated PHASE2

  8. Feb 2017 — Aug 2017 [monthly]

    Terminated PHASE2

  9. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE2

    First recorded

Oct 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Alexion Pharmaceuticals, Inc.
Data source: Alexion Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .