deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT00730782

Assessment of Three Formulations of the Candidate Vaccine AMA 1 in Healthy Dutch Adult Volunteers

Assessment of the Safety and Immunogenicity of Three Formulations of the Recombinant Pichia Pastoris Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545]), Blood-Stage Malaria Vaccine in Healthy Dutch Adult Volunteers : a Phase 1, Single- Blind, Randomised, Dose-Escalating, Unicentre Trial

Sponsor: Biomedical Primate Research Centre

Interventions PfAMA-1-FVO[25-545]
Updated 8 times since 2017 Last updated: Aug 7, 2008 Started: Nov 30, 2005 Primary completion: Sep 30, 2007 Completion: Aug 31, 2008
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Plasmodium Falciparum Malaria and is currently completed. Biomedical Primate Research Centre leads this study, which shows 8 recorded versions since 2005 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshotCompleted~Mar 2022 – ~Feb 2023 · 11 months · monthly snapshotCompleted~Feb 2023 – ~Sep 2023 · 7 months · monthly snapshotCompleted~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Sep 2023 — Jul 2024 [monthly]

    Completed PHASE1

  4. Feb 2023 — Sep 2023 [monthly]

    Completed PHASE1

  5. Mar 2022 — Feb 2023 [monthly]

    Completed PHASE1

Show 3 earlier versions
  1. Jan 2021 — Mar 2022 [monthly]

    Completed PHASE1

  2. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE1

  3. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE1

    First recorded

Nov 2005

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Biomedical Primate Research Centre
  • European Vaccine Initiative
  • GlaxoSmithKline
  • Radboud University Medical Center
  • Seppic
Data source: European Vaccine Initiative

For direct contact, visit the study record on ClinicalTrials.gov .