Completed NA INTERVENTIONAL 4-arm NCT00731003

The Effect of Serotonergic Modulation on Intestinal Permeability and Visceral Hypersensitivity in Healthy Individuals and Irritable Bowel Syndrome (IBS) Patients

The Effect of Serotonergic Modulation on Intestinal Permeability and Visceral Hypersensitivity in Healthy Individuals and IBS Patients

Sponsor: Maastricht University Medical Center

Conditions Irritable Bowel Syndrome

Interventions Acute tryptophan depletion Amino acid drink with tryptophan Oxitriptan Placebo capsule

Updated 5 times since 2017 Last updated: Nov 11, 2014 Started: Apr 30, 2009 Primary completion: May 31, 2011 Completion: May 31, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00731003, this NA trial focuses on Irritable Bowel Syndrome and remains completed. Sponsored by Maastricht University Medical Center, it has been updated 5 times since 2009, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

5 versions recorded

Sep 2024 — Present [monthly]

Completed NA
Jul 2024 — Sep 2024 [monthly]

Completed NA
Jan 2021 — Jul 2024 [monthly]

Completed NA
Jun 2018 — Jan 2021 [monthly]

Completed NA
Jan 2017 — Jun 2018 [monthly]

Completed NA

First recorded

Apr 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Maastricht University Medical Center
Top Institute Food and Nutrition

Data source: Maastricht University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Maastricht, Netherlands