Completed PHASE2 INTERVENTIONAL 2-arm NCT00743002

A Trial of TT223 in Patients With Type 2 Diabetes Who Are Taking Metformin and/or Thiazolidinedione

A Multi-center, Double-blind, Randomized, Placebo-controlled Study of TT223 in Patients With Type 2 Diabetes Treated With Metformin and/or TZD

Sponsor: OPKO Health, Inc.

Conditions Diabetes Mellitus, Type 2

Interventions Placebo with Metformin and/or TZD TT223 with Metformin and/or TZD

Updated 9 times since 2017 Last updated: Jun 13, 2013 Started: Aug 31, 2008 Primary completion: Dec 31, 2009 Completion: Dec 31, 2009

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Diabetes Mellitus, Type 2, this trial is completed. The trial is conducted by OPKO Health, Inc. and has accumulated 9 data snapshots since 2008. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

9 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Apr 2022 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Apr 2022 [monthly]

Completed PHASE2

▶ Show 4 earlier versions

Oct 2019 — Jan 2021 [monthly]

Completed PHASE2
Jun 2018 — Oct 2019 [monthly]

Completed PHASE2
Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Aug 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

OPKO Health, Inc.

Data source: OPKO Health, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Artesia, United States , Asheboro, United States , Athens, United States , Bensalem, United States , Bloomingdale, United States , Clifton, United States , Corpus Christi, United States , Dallas, United States , DeLand, United States , Grand Rapids, United States and 10 more locations