deltatrials
Completed PHASE2 INTERVENTIONAL 4-arm NCT00752323

Imaging Procedure Using ALA in Finding Residual Tumor in Grade IV Malignant Astrocytoma

Fluorescence-Guided Detection of Malignant Gliomas: A Dose Ranging Study Using 5-Aminolevulinic Acid (ALA) Induced Protoporphyrin (PpIX) in a Multicenter Phase II Clinical Trial

Sponsor: Andrew Sloan, MD

Conditions Brain and Central Nervous System Tumors
Interventions Surgical Resection aminolevulinic acid
Updated 13 times since 2017 Last updated: Sep 13, 2021 Started: Dec 8, 2009 Primary completion: Sep 15, 2018 Completion: Oct 14, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Brain and Central Nervous System Tumors, this trial is completed. The trial is conducted by Andrew Sloan, MD and has accumulated 13 data snapshots since 2009. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshot~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~Sep 2019 · 5 months · monthly snapshot~Sep 2019 – ~Dec 2019 · 3 months · monthly snapshot~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Jul 2024 · 33 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 24 months · monthly snapshot

Change History

13 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Oct 2021 — Jul 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Oct 2021 [monthly]

    Completed PHASE2

  5. Dec 2019 — Jan 2021 [monthly]

    Completed PHASE2

▶ Show 8 earlier versions

  1. Sep 2019 — Dec 2019 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  2. Apr 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  3. Feb 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  4. Nov 2018 — Feb 2019 [monthly]

    Recruiting PHASE2

  5. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  6. Jul 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  7. Feb 2017 — Jul 2017 [monthly]

    Recruiting PHASE2

  8. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Dec 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Andrew Sloan, MD
Data source: Case Comprehensive Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations