Completed PHASE3 INTERVENTIONAL 4-arm NCT00754988

A Study of Taspoglutide Versus Sitagliptin for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin.

A Multicenter, Randomized, Double-dummy, Placebo and Active-controlled Study to Assess the Safety, Tolerability and Effect of Taspoglutide on Glycemic Control Compared to Sitagliptin and Placebo in Patients With Type II Diabetes Mellitus Inadequately Controlled With Metformin.

Sponsor: Hoffmann-La Roche

Conditions Diabetes Mellitus Type 2

Interventions Metformin Placebo (matching sitagliptin) Placebo (matching taspoglutide) Sitagliptin Taspoglutide

Updated 8 times since 2017 Last updated: Nov 3, 2016 Started: Oct 31, 2008 Primary completion: Mar 31, 2011 Completion: Mar 31, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00754988, this PHASE3 trial focuses on Diabetes Mellitus Type 2 and remains completed. Sponsored by Hoffmann-La Roche, it has been updated 8 times since 2008, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Apr 2022 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Apr 2022 [monthly]

Completed PHASE3

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Oct 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Hoffmann-La Roche

Data source: Hoffmann-La Roche

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adelaide, Australia , Aliquippa, United States , Almería, Spain , Anderson, United States , Augusta, United States , Bacarot Alicant, Spain , Baltimore, United States , Bangkok, Thailand , Basel, Switzerland , Beaver, United States and 126 more locations