deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 3-arm NCT00799058

A Safety Study of Two Dapivirine (TMC120) Vaginal Gels in the United States

A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED PHASE I/II TRIAL TO EVALUATE THE SAFETY OF DAPIVIRINE GEL 4759, 0.05% 2.5g AND DAPIVIRINE GEL 4789, 0.05% 2.5g FORMULATIONS AS COMPARED TO THE VAGINAL HEC-BASED UNIVERSAL PLACEBO GEL, 2.5g IN HEALTHY HIV-NEGATIVE WOMEN

Sponsor: International Partnership for Microbicides, Inc.

Updated 12 times since 2017 Last updated: Oct 24, 2022 Started: Jul 6, 2009 Primary completion: Jan 8, 2011 Completion: Jan 8, 2011
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00799058, this PHASE1/PHASE2 trial focuses on HIV-1 Infections and remains completed. Sponsored by International Partnership for Microbicides, Inc., it has been updated 12 times since 2009, reflecting substantial change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshotCompleted~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotCompleted~Mar 2021 – ~Apr 2022 · 13 months · monthly snapshotCompleted~Apr 2022 – ~May 2022 · 30 days · monthly snapshotCompleted~May 2022 – ~Jul 2022 · 2 months · monthly snapshotCompleted~Jul 2022 – ~Nov 2022 · 4 months · monthly snapshotCompleted~Nov 2022 – ~Jul 2024 · 20 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Nov 2022 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Jul 2022 — Nov 2022 [monthly]

    Completed PHASE1_PHASE2

  5. May 2022 — Jul 2022 [monthly]

    Completed PHASE1_PHASE2

Show 7 earlier versions
  1. Apr 2022 — May 2022 [monthly]

    Completed PHASE1_PHASE2

  2. Mar 2021 — Apr 2022 [monthly]

    Completed PHASE1_PHASE2

    Phase: PHASE3PHASE1_PHASE2

  3. Jan 2021 — Mar 2021 [monthly]

    Completed PHASE3

  4. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

  5. Oct 2017 — Jun 2018 [monthly]

    Completed PHASE3

    Phase: PHASE1_PHASE2PHASE3

  6. Feb 2017 — Oct 2017 [monthly]

    Completed PHASE1_PHASE2

  7. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE1_PHASE2

    First recorded

Jul 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • International Partnership for Microbicides, Inc.
Data source: International Partnership for Microbicides, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .