deltatrials
Completed PHASE4 INTERVENTIONAL 3-arm NCT00807326

A Comparison of Three Medications to Treat Diarrhea in Adults.

A Randomized, Parallel Group Comparison of Loperamide/Simeticone Caplet, Loperamide/Simeticone Chewable Tablet (IMODIUM® PLUS) and a Probiotic (Saccharomyces Boulardii) in the Treatment of Acute Diarrhea in Adults

Sponsor: McNeil AB

Conditions Diarrhea
Interventions Loperamide/simeticone 2 mg/125 mg caplets Loperamide/simeticone 2 mg/125 mg chewable tablets Probiotic Saccharomyces boulardii 250 mg capsules
Updated 6 times since 2017 Last updated: Jul 6, 2012 Started: Nov 30, 2008 Primary completion: Aug 31, 2009 Completion: Nov 30, 2009
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00807326, this PHASE4 trial focuses on Diarrhea and remains completed. Sponsored by McNeil AB, it has been updated 6 times since 2008, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

6 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE4

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE4

▶ Show 1 earlier version

  1. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE4

    First recorded

Nov 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • McNeil AB
Data source: Johnson & Johnson Consumer and Personal Products Worldwide

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations