deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT00819780

PEAK: Panitumumab Plus mFOLFOX6 vs. Bevacizumab Plus mFOLFOX6 for First Line Treatment of Metastatic Colorectal Cancer (mCRC) Patients With Wild-Type Kirsten Rat Sarcoma-2 Virus (KRAS) Tumors

A Randomized, Multicenter, Phase 2 Study to Compare the Efficacy of Panitumumab in Combination With mFOLFOX6 to the Efficacy of Bevacizumab in Combination With mFOLFOX6 in Patients With Previously Untreated, KRAS Wild-Type, Unresectable, Metastatic Colorectal Cancer

Sponsor: Amgen

Updated 12 times since 2017 Last updated: Nov 10, 2022 Started: Apr 24, 2009 Primary completion: May 30, 2012 Completion: Jul 7, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Colon Cancer and Colorectal Cancer and is currently completed. Amgen leads this study, which shows 12 recorded versions since 2009 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Dec 2017 · 10 months · monthly snapshotCompleted~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotCompleted~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotCompleted~Sep 2018 – ~Sep 2019 · 12 months · monthly snapshotCompleted~Sep 2019 – ~Jan 2021 · 16 months · monthly snapshotCompleted~Jan 2021 – ~Sep 2022 · 20 months · monthly snapshotCompleted~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshotCompleted~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  5. Sep 2022 — Jan 2023 [monthly]

    Completed PHASE2

Show 7 earlier versions
  1. Jan 2021 — Sep 2022 [monthly]

    Completed PHASE2

  2. Sep 2019 — Jan 2021 [monthly]

    Completed PHASE2

  3. Sep 2018 — Sep 2019 [monthly]

    Completed PHASE2

  4. Jun 2018 — Sep 2018 [monthly]

    Completed PHASE2

  5. Dec 2017 — Jun 2018 [monthly]

    Completed PHASE2

  6. Feb 2017 — Dec 2017 [monthly]

    Completed PHASE2

  7. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Apr 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Amgen
Data source: Amgen

For direct contact, visit the study record on ClinicalTrials.gov .