deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT00823082

Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass

A Prospective Randomized Pilot Study to Evaluate the Effect of Preoperative Antithrombin Supplementation on Postoperative Levels of Antithrombin in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass

Sponsor: Instituto Grifols, S.A.

Interventions Antithrombin III
Updated 10 times since 2017 Last updated: Aug 10, 2016 Started: Jun 30, 2009 Primary completion: Jun 30, 2011 Completion: Sep 30, 2011
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00823082, this PHASE2 trial focuses on Acquired Antithrombin III Deficiency and Coronary Artery Bypass and remains completed. Sponsored by Instituto Grifols, S.A., it has been updated 10 times since 2009, reflecting substantial change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~May 2019 · 11 months · monthly snapshotCompleted~May 2019 – ~Jan 2021 · 20 months · monthly snapshotCompleted~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshotCompleted~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotCompleted~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 11 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  5. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

Show 5 earlier versions
  1. Jan 2021 — Dec 2022 [monthly]

    Completed PHASE2

  2. May 2019 — Jan 2021 [monthly]

    Completed PHASE2

  3. Jun 2018 — May 2019 [monthly]

    Completed PHASE2

  4. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE2

  5. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Jun 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Instituto Grifols, S.A.
Data source: Grifols Biologicals, LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations