deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT00828672

Neoadjuvant Bevacizumab, Capecitabine and Radiation Therapy With or Without Oxaliplatin Locally Advanced Rectal Cancer (AXEBEAM)

A Randomized Phase II Study of Bevacizumab, Capecitabine and Radiation Therapy With or Without Oxaliplatin in the Preoperative Treatment of Locally Advanced Rectal Cancer

Sponsor: Universitaire Ziekenhuizen KU Leuven

Updated 11 times since 2017 Last updated: Jul 9, 2019 Started: Jun 30, 2009 Primary completion: Mar 31, 2014 Completion: Mar 31, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Locally Advanced Rectal Cancer and is currently completed. Universitaire Ziekenhuizen KU Leuven leads this study, which shows 11 recorded versions since 2009 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Jun 2017 · 5 months · monthly snapshotActive Not Recruiting~Jun 2017 – ~Jun 2018 · 12 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Jun 2019 · 12 months · monthly snapshotActive Not Recruiting~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshotUnknown Status~Aug 2019 – ~Jan 2021 · 17 months · monthly snapshotCompleted~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotCompleted~Dec 2021 – ~Oct 2022 · 10 months · monthly snapshotCompleted~Oct 2022 – ~Jul 2024 · 21 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Oct 2022 — Jul 2024 [monthly]

    Completed PHASE2

  5. Dec 2021 — Oct 2022 [monthly]

    Completed PHASE2

Show 6 earlier versions
  1. Jan 2021 — Dec 2021 [monthly]

    Completed PHASE2

  2. Aug 2019 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Unknown StatusCompleted

  3. Jun 2019 — Aug 2019 [monthly]

    Unknown Status PHASE2

    Status: Active Not RecruitingUnknown Status

  4. Jun 2018 — Jun 2019 [monthly]

    Active Not Recruiting PHASE2

  5. Jun 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  6. Jan 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Jun 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Universitaire Ziekenhuizen KU Leuven
Data source: Universitaire Ziekenhuizen KU Leuven

For direct contact, visit the study record on ClinicalTrials.gov .