Unknown PHASE2 INTERVENTIONAL 3-arm NCT00865917

Cardiovascular Effects of Selective I(f)-Channel Blockade

Einfluss Selektiver I(f)-Blockade Auf Orthostase-Toleranz Und Sympathikusaktivität Bei Gesunden

Sponsor: Charite University, Berlin, Germany

Conditions Postural Orthostatic Tachycardia Syndrome

Interventions I(f)-blocker (ivabradine) Placebo beta-blocker (Metoprolol)

Updated 5 times since 2017 Last updated: Mar 18, 2009 Started: Nov 30, 2008 Primary completion: Nov 30, 2010 Completion: Dec 31, 2010

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Postural Orthostatic Tachycardia Syndrome and is currently ongoing. Charite University, Berlin, Germany leads this study, which shows 5 recorded versions since 2008 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

5 versions recorded

Sep 2025 — Present [monthly]

Unknown PHASE2
Sep 2024 — Sep 2025 [monthly]

Unknown PHASE2
Jul 2024 — Sep 2024 [monthly]

Unknown PHASE2

Status: Unknown Status → Unknown
Jan 2021 — Jul 2024 [monthly]

Unknown Status PHASE2
Jan 2017 — Jan 2021 [monthly]

Unknown Status PHASE2

First recorded

Nov 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Charite University, Berlin, Germany
Hannover Medical School

Data source: Hannover Medical School

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Berlin, Germany
• Hanover, Germany