deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT00879437

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

A Phase 2 Study of Valproic Acid and Radiation, Followed by Maintenance Valproic Acid and Bevacizumab in Children With Newly Diagnosed High-grade Gliomas or Brainstem Gliomas

Sponsor: Baylor College of Medicine

Updated 10 times since 2017 Last updated: Jun 30, 2021 Started: Sep 1, 2009 Primary completion: Aug 30, 2015 Completion: Oct 2, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00879437, this PHASE2 trial focuses on Anaplastic Astrocytoma and Brainstem Glioma and remains completed. Sponsored by Baylor College of Medicine, it has been updated 10 times since 2009, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Sep 2019 · 15 months · monthly snapshotActive Not Recruiting~Sep 2019 – ~Feb 2020 · 5 months · monthly snapshotUnknown Status~Feb 2020 – ~Dec 2020 · 10 months · monthly snapshotActive Not Recruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotCompleted~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotCompleted~Sep 2021 – ~Jul 2024 · 34 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 21 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Sep 2021 — Jul 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Sep 2021 [monthly]

    Completed PHASE2

  5. Dec 2020 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

Show 5 earlier versions
  1. Feb 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: Unknown StatusActive Not Recruiting

  2. Sep 2019 — Feb 2020 [monthly]

    Unknown Status PHASE2

    Status: Active Not RecruitingUnknown Status

  3. Jun 2018 — Sep 2019 [monthly]

    Active Not Recruiting PHASE2

  4. Feb 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  5. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Sep 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Baylor College of Medicine
  • Cook Children's Medical Center
  • M.D. Anderson Cancer Center
  • The University of Texas Health Science Center at San Antonio
  • University of Oklahoma
  • University of Texas, Southwestern Medical Center at Dallas
Data source: Baylor College of Medicine

For direct contact, visit the study record on ClinicalTrials.gov .