deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT00942331

Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer

A Randomized Double-Blinded Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients With Advanced Transitional Cell Carcinoma

Sponsor: National Cancer Institute (NCI)

Updated 48 times since 2017 Last updated: Oct 12, 2023 Started: Jul 15, 2009 Primary completion: Nov 2, 2018 Completion: Jun 15, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Advanced Urothelial Carcinoma and Metastatic Bladder Urothelial Carcinoma, this trial is completed. The trial is conducted by National Cancer Institute (NCI) and has accumulated 48 data snapshots since 2009. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Oct 2017 · 4 months · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Mar 2020 · 4 months · monthly snapshot~Mar 2020 – ~May 2020 · 2 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Mar 2022 · 5 months · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshot~Jan 2023 – ~Nov 2023 · 10 months · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

48 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Nov 2023 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jan 2023 — Nov 2023 [monthly]

    Completed PHASE3

Show 43 earlier versions
  1. Sep 2022 — Jan 2023 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  2. Jun 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE3

  3. May 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE3

  4. Apr 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE3

  5. Mar 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

  6. Oct 2021 — Mar 2022 [monthly]

    Active Not Recruiting PHASE3

  7. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE3

  8. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

  9. Apr 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE3

  10. Mar 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE3

  11. Feb 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE3

  12. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE3

  13. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  14. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE3

  15. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  16. Sep 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE3

  17. Jul 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

  18. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE3

  19. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE3

  20. Mar 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE3

  21. Nov 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE3

  22. Sep 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE3

    Status: CompletedActive Not Recruiting

  23. Aug 2019 — Sep 2019 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  24. Jul 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE3

  25. Jun 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE3

  26. May 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE3

  27. Apr 2019 — May 2019 [monthly]

    Active Not Recruiting PHASE3

  28. Mar 2019 — Apr 2019 [monthly]

    Active Not Recruiting PHASE3

  29. Feb 2019 — Mar 2019 [monthly]

    Active Not Recruiting PHASE3

  30. Jan 2019 — Feb 2019 [monthly]

    Active Not Recruiting PHASE3

  31. Nov 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE3

  32. Oct 2018 — Nov 2018 [monthly]

    Active Not Recruiting PHASE3

  33. Sep 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE3

  34. Aug 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE3

  35. Jul 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE3

  36. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE3

  37. Dec 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

  38. Nov 2017 — Dec 2017 [monthly]

    Active Not Recruiting PHASE3

  39. Oct 2017 — Nov 2017 [monthly]

    Active Not Recruiting PHASE3

  40. Jun 2017 — Oct 2017 [monthly]

    Active Not Recruiting PHASE3

  41. May 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE3

  42. Feb 2017 — May 2017 [monthly]

    Active Not Recruiting PHASE3

  43. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Jul 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .