deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT00954915

Safety Study of the Monoclonal Antibody Teplizumab (MGA031) in Subjects With Moderate or More Severe Psoriasis

A Phase 2a, Open Label, Multiple-Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Teplizumab in Adults With Moderate or More Severe Psoriasis

Sponsor: Eli Lilly and Company

Conditions Psoriasis
Interventions teplizumab
Updated 12 times since 2017 Last updated: Feb 4, 2022 Started: Dec 31, 2009 Primary completion: Jul 31, 2010 Completion: Jul 31, 2010
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Injection site reaction met protocol-defined stopping criteria.

This PHASE1/PHASE2 trial investigates Psoriasis and is currently terminated or withdrawn. Eli Lilly and Company leads this study, which shows 12 recorded versions since 2009 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotTerminated~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshotTerminated~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshotTerminated~Mar 2022 – ~Dec 2022 · 9 months · monthly snapshotTerminated~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotTerminated~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 19 months · monthly snapshotTerminated~Jan 2026 – present · 3 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Jan 2026 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Sep 2024 — Present [monthly]

    Terminated PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

  5. Dec 2022 — Jan 2023 [monthly]

    Terminated PHASE1_PHASE2

Show 7 earlier versions
  1. Mar 2022 — Dec 2022 [monthly]

    Terminated PHASE1_PHASE2

  2. Jan 2022 — Mar 2022 [monthly]

    Terminated PHASE1_PHASE2

  3. Dec 2021 — Jan 2022 [monthly]

    Terminated PHASE1_PHASE2

  4. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE1_PHASE2

  5. Jun 2018 — Jan 2021 [monthly]

    Terminated PHASE1_PHASE2

  6. Feb 2017 — Jun 2018 [monthly]

    Terminated PHASE1_PHASE2

  7. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE1_PHASE2

    First recorded

Dec 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eli Lilly and Company
  • MacroGenics
Data source: MacroGenics

For direct contact, visit the study record on ClinicalTrials.gov .