Completed PHASE3 INTERVENTIONAL 2-arm NCT00988091

Investigation of 1.2% Sodium Hyaluronate for Treatment of Painful Chronic Osteoarthritis of the Knee

A 26 Week, Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Single Intra-Articular Injection 1.2% Sodium Hyaluronate for Treatment of Painful Osteoarthritis of the Knee, With Optional 26-Week Open-Label Safety Extension

Sponsor: Ferring Pharmaceuticals

Conditions Osteoarthritis of the Knee

Interventions 1.2% Sodium Hyaluronate Buffered Saline

Updated 7 times since 2017 Last updated: Jun 13, 2012 Started: Sep 30, 2009 Primary completion: Oct 31, 2010 Completion: Apr 30, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00988091, this PHASE3 trial focuses on Osteoarthritis of the Knee and remains completed. Sponsored by Ferring Pharmaceuticals, it has been updated 7 times since 2009, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Sep 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Ferring Pharmaceuticals

Data source: Ferring Pharmaceuticals

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aventura, United States , Bellevue, United States , Buena Park, United States , Burbank, United States , Englewood, United States , Fort Lauderdale, United States , Grapevine, United States , Homewood, United States , Hot Springs, United States , Houston, United States and 23 more locations