Completed PHASE1 INTERVENTIONAL 1-arm NCT00988767

Safety and Immunogenicity of a Naked DNA-based Vaccine Therapy in Patients With Chronic Hepatitis B (RBM99026)

Specific Vaccine Therapy in Chronic Hepatitis B Using a Naked DNA: Phase I Study Using a GMO

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Interventions DNA vaccine

Updated 6 times since 2017 Last updated: Sep 23, 2025 Started: Feb 28, 2001 Primary completion: Nov 30, 2003 Completion: Oct 31, 2004

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Chronic Hepatitis B and is currently completed. Institut National de la Santé Et de la Recherche Médicale, France leads this study, which shows 6 recorded versions since 2001 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

Change History

6 versions recorded

Oct 2025 — Present [monthly]

Completed PHASE1
Sep 2024 — Oct 2025 [monthly]

Completed PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1
Jun 2018 — Jan 2021 [monthly]

Completed PHASE1

▶ Show 1 earlier version

Jan 2017 — Jun 2018 [monthly]

Completed PHASE1

First recorded

Feb 2001

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Institut National de la Santé Et de la Recherche Médicale, France

Data source: Institut National de la Santé Et de la Recherche Médicale, France

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Paris, France