deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT01048138

Use of Biperiden for the Prevention of Post-traumatic Epilepsy

Use of Biperiden as a Disease Modifying Agent After Traumatic Brain Injury: a Placebo Controlled, Randomized, Double Blind Study

Sponsor: Federal University of São Paulo

Updated 12 times since 2017 Last updated: Jan 27, 2023 Started: Jan 31, 2018 Primary completion: Dec 2, 2022 Completion: Dec 2, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Recruitment and funding issues, together with the event of the SARS-CoV-2 pandemic prompted an adjustment in the study design to stop enrollment at 123 patients.

A PHASE3 clinical study on Traumatic Brain Injury, this trial is terminated or withdrawn. The trial is conducted by Federal University of São Paulo and has accumulated 12 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshotRecruiting~Aug 2017 – ~Mar 2018 · 7 months · monthly snapshotRecruiting~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshotRecruiting~Jun 2018 – ~Apr 2019 · 10 months · monthly snapshotRecruiting~Apr 2019 – ~Mar 2020 · 11 months · monthly snapshotRecruiting~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshotRecruiting~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotRecruiting~Sep 2021 – ~Feb 2023 · 17 months · monthly snapshotRecruiting~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Feb 2023 — Jul 2024 [monthly]

    Terminated PHASE3

    Status: RecruitingTerminated

  5. Sep 2021 — Feb 2023 [monthly]

    Recruiting PHASE3

Show 7 earlier versions
  1. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  2. Mar 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  3. Apr 2019 — Mar 2020 [monthly]

    Recruiting PHASE3

  4. Jun 2018 — Apr 2019 [monthly]

    Recruiting PHASE3

  5. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  6. Aug 2017 — Mar 2018 [monthly]

    Recruiting PHASE3

  7. Jan 2017 — Aug 2017 [monthly]

    Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Federal University of São Paulo
  • University of Sao Paulo
Data source: Federal University of São Paulo

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations