Completed PHASE2 INTERVENTIONAL 4-arm NCT01073228

Safety and Cognitive Function Study of EVP-6124 in Patients With Mild to Moderate Alzheimer's Disease

A Randomized, Double-blind, Placebo-Controlled, Parallel, 24-Week, Phase 2 Study of Three Different Doses of an Alpha-7 Nicotinic Acetylcholine Receptor Agonist (EVP-6124) or Placebo in Subjects With Mild to Moderate Probable Alzheimer's Disease

Sponsor: FORUM Pharmaceuticals Inc

Conditions Alzheimer's Disease Central Nervous System Diseases Cognition

Interventions EVP-6124 Placebo

Updated 8 times since 2017 Last updated: Mar 28, 2014 Started: Apr 30, 2010 Primary completion: Nov 30, 2011 Completion: Feb 29, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01073228, this PHASE2 trial focuses on Alzheimer's Disease and Central Nervous System Diseases and remains completed. Sponsored by FORUM Pharmaceuticals Inc, it has been updated 8 times since 2010, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Apr 2022 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Apr 2022 [monthly]

Completed PHASE2

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE2
Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Apr 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

FORUM Pharmaceuticals Inc
INC Research Limited

Data source: FORUM Pharmaceuticals Inc

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Belgrade, Serbia , Bennington, United States , Brooklyn, United States , Brooksville, United States , Bucharest, Romania , Chino, United States , Columbus, United States , Costa Mesa, United States , Dallas, United States , Delray Beach, United States and 33 more locations