deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT01077297

Tezosentan in Pulmonary Arterial Hypertension

Multicenter, Open-label, Non-comparative, Proof-of-concept, Phase 2a Study to Evaluate the Effect of a Single Infusion of Tezosentan on Pulmonary Vascular Resistance in Patients With Stable, Chronic Pulmonary Arterial Hypertension, Currently Not Treated With Endothelin Receptor Antagonists, Phosphodiesterase-5 Inhibitors or Prostacyclines

Sponsor: Idorsia Pharmaceuticals Ltd.

Interventions Tezosentan
Updated 9 times since 2017 Last updated: Jul 6, 2018 Started: Aug 31, 2010 Primary completion: Nov 30, 2010 Completion: Sep 30, 2011
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Due to slow recruitment, the study was prematurely discontinued

This PHASE2 trial investigates Pulmonary Arterial Hypertension and is currently terminated or withdrawn. Idorsia Pharmaceuticals Ltd. leads this study, which shows 9 recorded versions since 2010 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotTerminated~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshotTerminated~Aug 2018 – ~Jan 2021 · 29 months · monthly snapshotTerminated~Jan 2021 – ~Apr 2022 · 15 months · monthly snapshotTerminated~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Apr 2022 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Jan 2021 — Apr 2022 [monthly]

    Terminated PHASE2

Show 4 earlier versions
  1. Aug 2018 — Jan 2021 [monthly]

    Terminated PHASE2

  2. Jun 2018 — Aug 2018 [monthly]

    Terminated PHASE2

  3. Feb 2017 — Jun 2018 [monthly]

    Terminated PHASE2

  4. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE2

    First recorded

Aug 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Idorsia Pharmaceuticals Ltd.
Data source: Idorsia Pharmaceuticals Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .