deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT01083615

A Study Evaluating the Pain Palliation Benefit of Adding Custirsen to Docetaxel Retreatment or Cabazitaxel as Second Line Therapy in Men With Metastatic Castrate Resistant Prostate Cancer (mCRPC)

A Randomized, Placebo-Controlled, Double-Blind, Phase 3 Study Evaluating the Pain Palliation Benefit of Adding Custirsen to a Taxane for Second-Line Chemotherapy in Men With Castrate Resistance Prostate Cancer

Sponsor: Achieve Life Sciences

Updated 9 times since 2017 Last updated: Oct 7, 2016 Started: Mar 31, 2010 Primary completion: Mar 31, 2013 Completion: Mar 31, 2013
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Unable to enroll due to criteria for stable baseline pain

This PHASE3 trial investigates Castrate-Resistant Prostate Cancer and Hormone Refractory Prostate Cancer and is currently terminated or withdrawn. Achieve Life Sciences leads this study, which shows 9 recorded versions since 2010 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshotTerminated~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshotTerminated~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotTerminated~Jan 2021 – ~Apr 2022 · 15 months · monthly snapshotTerminated~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Apr 2022 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Jan 2021 — Apr 2022 [monthly]

    Terminated PHASE3

Show 4 earlier versions
  1. Jun 2018 — Jan 2021 [monthly]

    Terminated PHASE3

  2. Sep 2017 — Jun 2018 [monthly]

    Terminated PHASE3

  3. Feb 2017 — Sep 2017 [monthly]

    Terminated PHASE3

  4. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

Mar 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Achieve Life Sciences
  • Teva Pharmaceuticals USA
Data source: Achieve Life Sciences

For direct contact, visit the study record on ClinicalTrials.gov .