Completed PHASE2 INTERVENTIONAL 2-arm NCT01113957

A Trial of ABT-888 in Combination With Temozolomide Versus Pegylated Liposomal Doxorubicin Alone in Ovarian Cancer

A Phase 2 Randomized Clinical Trial of ABT-888 in Combination With Temozolomide Versus Pegylated Liposomal Doxorubicin Alone in Subjects With Recurrent High Grade Serous Ovarian Cancer

Sponsor: AbbVie (prior sponsor, Abbott)

Conditions Ovarian Cancer

Interventions ABT-888 pegylated liposomal doxorubicin temozolomide

Updated 9 times since 2017 Last updated: Jun 1, 2018 Started: Mar 31, 2010 Primary completion: Jun 30, 2013 Completion: Jun 30, 2013

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Ovarian Cancer and is currently completed. AbbVie (prior sponsor, Abbott) leads this study, which shows 9 recorded versions since 2010 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

9 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Apr 2022 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Apr 2022 [monthly]

Completed PHASE2

▶ Show 4 earlier versions

Jul 2018 — Jan 2021 [monthly]

Completed PHASE2
Jun 2018 — Jul 2018 [monthly]

Completed PHASE2
Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Mar 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

AbbVie (prior sponsor, Abbott)

Data source: AbbVie

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adelaide, Australia , Albuquerque, United States , Auckland, New Zealand , Bedford Park, Australia , Budapest, Hungary , Chapel Hill, United States , Chicago, United States , Duarte, United States , East Melbourne, Australia , Edmonton, Canada and 22 more locations