Completed PHASE1 INTERVENTIONAL 2-arm NCT01123070

TL011 in Severe, Active Rheumatoid Arthritis Patients

A Phase Ib Study Evaluating Safety, Pharmacokinetic and Pharmacodynamic Profiles of a Single Course of TL011 Infusions in Subjects With Severe, Active Rheumatoid Arthritis

Sponsor: Teva Pharmaceutical Industries, Ltd.

Conditions Rheumatoid Arthritis

Interventions MabThera infusions TL011, anti CD20, for the treatment of rheumatoid arthritis

Updated 8 times since 2017 Last updated: Sep 7, 2021 Started: Feb 5, 2010 Primary completion: Apr 23, 2012 Completion: Apr 23, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01123070, this PHASE1 trial focuses on Rheumatoid Arthritis and remains completed. Sponsored by Teva Pharmaceutical Industries, Ltd., it has been updated 8 times since 2010, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE1
Sep 2024 — Sep 2025 [monthly]

Completed PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1
Jan 2022 — Jul 2024 [monthly]

Completed PHASE1
Nov 2021 — Jan 2022 [monthly]

Completed PHASE1

Phase: PHASE1_PHASE2 → PHASE1

▶ Show 3 earlier versions

Jan 2021 — Nov 2021 [monthly]

Completed PHASE1_PHASE2
Jun 2018 — Jan 2021 [monthly]

Completed PHASE1_PHASE2
Jan 2017 — Jun 2018 [monthly]

Completed PHASE1_PHASE2

First recorded

Feb 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Teva Pharmaceutical Industries, Ltd.

Data source: Teva Branded Pharmaceutical Products R&D, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Barakaldo, Spain , Budapest, Hungary , Debrecen, Hungary , Florence, Italy , Genova, Italy , Guadalajara, Spain , Madrid, Spain , Manchester, United Kingdom , Pavia, Italy , Pilsen, Czechia and 7 more locations