Completed PHASE3 INTERVENTIONAL 3-arm NCT01135069

Bioequivalence Study of Generic Tretinoin 0.1% Microsphere Gel, 0.1% Retin-A Micro® and Placebo

Sponsor: Spear Pharmaceuticals

Conditions Acne

Interventions Brand Retin-A Micro tretinoin microsphere gel 0.1% Tretinoin microsphere 0.1% placebo microsphere gel

Updated 10 times since 2017 Last updated: Oct 15, 2014 Started: Oct 31, 2009 Primary completion: Apr 30, 2010 Completion: Apr 30, 2010

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Acne, this trial is completed. The trial is conducted by Spear Pharmaceuticals and has accumulated 10 data snapshots since 2009. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

10 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2023 — Jul 2024 [monthly]

Completed PHASE3
Dec 2022 — Jan 2023 [monthly]

Completed PHASE3

▶ Show 5 earlier versions

Dec 2021 — Dec 2022 [monthly]

Completed PHASE3
Jan 2021 — Dec 2021 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Oct 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Spear Pharmaceuticals

Data source: Spear Pharmaceuticals

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Land O' Lakes, United States