Completed PHASE3 INTERVENTIONAL 2-arm NCT01166438

Anticholinergic vs. Botox Comparison Study (ABC)

Efficacy and Impact of Botulinum Toxin A Versus Anticholinergic Therapy for the Treatment of Bothersome Urge Urinary Incontinence

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions Overactive Bladder Urge Urinary Incontinence

Interventions Botulinum toxin A (Botox A®) Solifenacin 10mg Solifenacin 5mg Trospium chloride

Updated 7 times since 2017 Last updated: Apr 30, 2018 Started: Mar 31, 2010 Primary completion: May 31, 2012 Completion: May 31, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01166438, this PHASE3 trial focuses on Overactive Bladder and Urge Urinary Incontinence and remains completed. Sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), it has been updated 7 times since 2010, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3
Dec 2017 — Jun 2018 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Feb 2017 — Dec 2017 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Mar 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NICHD Pelvic Floor Disorders Network

Data source: NICHD Pelvic Floor Disorders Network

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Birmingham, United States , Cleveland, United States , Dallas, United States , Dearborn, United States , Durham, United States , La Jolla, United States , Maywood, United States , Pittsburgh, United States , Royal Oak, United States , Salt Lake City, United States and 1 more location