Completed PHASE3 INTERVENTIONAL 3-arm NCT01188265

Add-on Dextromethorphan in Bipolar Disorders (DM)

Dextromethorphan Enhances the Therapeutic Efficacy of Valoproate in Bipolar Disorder Patients

Sponsor: National Cheng-Kung University Hospital

Interventions Dextromethorphan 30 mg Dextromethorphan 60 mg per day Placebo Valproate

Updated 7 times since 2017 Last updated: Sep 16, 2013 Started: Jun 30, 2007 Primary completion: Dec 31, 2010 Completion: Jun 30, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Bipolar Disorder, this trial is completed. The trial is conducted by National Cheng-Kung University Hospital and has accumulated 7 data snapshots since 2007. Psychiatric clinical trials are essential for establishing evidence-based treatment standards.

Status Flow

Change History

7 versions recorded

Dec 2025 — Present [monthly]

Completed PHASE3
Sep 2025 — Dec 2025 [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE3
Jan 2017 — Jun 2018 [monthly]

Completed PHASE3

First recorded

Jun 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Cheng-Kung University Hospital
National Health Research Institutes, Taiwan
TTY Biopharm

Data source: National Cheng-Kung University Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Tainan, Taiwan