deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT01294332

Effect of Aerobic Exercise Training on Cardiorespiratory Function in Patients With Traumatic Brain Injury

Effect of Aerobic Exercise Training on Cardiorespiratory Fitness in Patients With Traumatic Brain Injury

Sponsor: Center for Neuroscience and Regenerative Medicine (CNRM)

Conditions Exercise Fatigue Physical Fitness Traumatic Brain Injury
Interventions Aerobic Exercise Training
Updated 64 times since 2017 Last updated: Mar 6, 2026 Started: May 26, 2011 Primary completion: Dec 31, 2013 Completion: Feb 11, 2014
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Exercise and Fatigue and is currently completed. Center for Neuroscience and Regenerative Medicine (CNRM) leads this study, which shows 64 recorded versions since 2011 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Mar 2019 · 6 months · monthly snapshot~Mar 2019 – ~May 2019 · 2 months · monthly snapshot~May 2019 – ~Jul 2019 · 2 months · monthly snapshot~Jul 2019 – ~Jan 2020 · 6 months · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~May 2020 · 2 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Dec 2020 · 3 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Jan 2022 · 2 months · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~Jul 2023 · 3 months · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Nov 2023 · 2 months · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Dec 2024 · 2 months · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshot~Mar 2026 – present · 4 months · monthly snapshot

Change History

64 versions recorded

  1. Mar 2026 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Feb 2026 — Mar 2026 [monthly]

    Completed PHASE1/PHASE2

  3. Jan 2026 — Feb 2026 [monthly]

    Completed PHASE1/PHASE2

  4. Dec 2025 — Jan 2026 [monthly]

    Completed PHASE1/PHASE2

  5. Sep 2025 — Dec 2025 [monthly]

    Completed PHASE1/PHASE2

▶ Show 59 earlier versions

  1. Aug 2025 — Sep 2025 [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2025 — Aug 2025 [monthly]

    Completed PHASE1/PHASE2

  3. Jun 2025 — Jul 2025 [monthly]

    Completed PHASE1/PHASE2

  4. Apr 2025 — Jun 2025 [monthly]

    Completed PHASE1/PHASE2

  5. Mar 2025 — Apr 2025 [monthly]

    Completed PHASE1/PHASE2

  6. Feb 2025 — Mar 2025 [monthly]

    Completed PHASE1/PHASE2

  7. Jan 2025 — Feb 2025 [monthly]

    Completed PHASE1/PHASE2

  8. Dec 2024 — Jan 2025 [monthly]

    Completed PHASE1/PHASE2

  9. Oct 2024 — Dec 2024 [monthly]

    Completed PHASE1/PHASE2

  10. Sep 2024 — Oct 2024 [monthly]

    Completed PHASE1/PHASE2

  11. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

  12. Jul 2024 — Aug 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  13. Jun 2024 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  14. May 2024 — Jun 2024 [monthly]

    Completed PHASE1_PHASE2

  15. Apr 2024 — May 2024 [monthly]

    Completed PHASE1_PHASE2

  16. Mar 2024 — Apr 2024 [monthly]

    Completed PHASE1_PHASE2

  17. Feb 2024 — Mar 2024 [monthly]

    Completed PHASE1_PHASE2

  18. Jan 2024 — Feb 2024 [monthly]

    Completed PHASE1_PHASE2

  19. Dec 2023 — Jan 2024 [monthly]

    Completed PHASE1_PHASE2

  20. Nov 2023 — Dec 2023 [monthly]

    Completed PHASE1_PHASE2

  21. Sep 2023 — Nov 2023 [monthly]

    Completed PHASE1_PHASE2

  22. Aug 2023 — Sep 2023 [monthly]

    Completed PHASE1_PHASE2

  23. Jul 2023 — Aug 2023 [monthly]

    Completed PHASE1_PHASE2

  24. Apr 2023 — Jul 2023 [monthly]

    Completed PHASE1_PHASE2

  25. Mar 2023 — Apr 2023 [monthly]

    Completed PHASE1_PHASE2

  26. Feb 2023 — Mar 2023 [monthly]

    Completed PHASE1_PHASE2

  27. Jan 2023 — Feb 2023 [monthly]

    Completed PHASE1_PHASE2

  28. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE1_PHASE2

  29. Nov 2022 — Dec 2022 [monthly]

    Completed PHASE1_PHASE2

  30. Sep 2022 — Nov 2022 [monthly]

    Completed PHASE1_PHASE2

  31. Jun 2022 — Sep 2022 [monthly]

    Completed PHASE1_PHASE2

  32. May 2022 — Jun 2022 [monthly]

    Completed PHASE1_PHASE2

  33. Apr 2022 — May 2022 [monthly]

    Completed PHASE1_PHASE2

  34. Mar 2022 — Apr 2022 [monthly]

    Completed PHASE1_PHASE2

  35. Feb 2022 — Mar 2022 [monthly]

    Completed PHASE1_PHASE2

  36. Jan 2022 — Feb 2022 [monthly]

    Completed PHASE1_PHASE2

  37. Nov 2021 — Jan 2022 [monthly]

    Completed PHASE1_PHASE2

  38. Oct 2021 — Nov 2021 [monthly]

    Completed PHASE1_PHASE2

  39. Sep 2021 — Oct 2021 [monthly]

    Completed PHASE1_PHASE2

  40. Jun 2021 — Sep 2021 [monthly]

    Completed PHASE1_PHASE2

  41. May 2021 — Jun 2021 [monthly]

    Completed PHASE1_PHASE2

  42. Apr 2021 — May 2021 [monthly]

    Completed PHASE1_PHASE2

  43. Jan 2021 — Apr 2021 [monthly]

    Completed PHASE1_PHASE2

  44. Dec 2020 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

  45. Sep 2020 — Dec 2020 [monthly]

    Completed PHASE1_PHASE2

  46. Aug 2020 — Sep 2020 [monthly]

    Completed PHASE1_PHASE2

  47. Jul 2020 — Aug 2020 [monthly]

    Completed PHASE1_PHASE2

  48. Jun 2020 — Jul 2020 [monthly]

    Completed PHASE1_PHASE2

  49. May 2020 — Jun 2020 [monthly]

    Completed PHASE1_PHASE2

  50. Mar 2020 — May 2020 [monthly]

    Completed PHASE1_PHASE2

  51. Jan 2020 — Mar 2020 [monthly]

    Completed PHASE1_PHASE2

  52. Jul 2019 — Jan 2020 [monthly]

    Completed PHASE1_PHASE2

  53. May 2019 — Jul 2019 [monthly]

    Completed PHASE1_PHASE2

  54. Mar 2019 — May 2019 [monthly]

    Completed PHASE1_PHASE2

  55. Sep 2018 — Mar 2019 [monthly]

    Completed PHASE1_PHASE2

  56. Aug 2018 — Sep 2018 [monthly]

    Completed PHASE1_PHASE2

  57. Jul 2018 — Aug 2018 [monthly]

    Completed PHASE1_PHASE2

  58. Jun 2018 — Jul 2018 [monthly]

    Completed PHASE1_PHASE2

  59. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE1_PHASE2

    First recorded

May 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Center for Neuroscience and Regenerative Medicine (CNRM)
  • National Institutes of Health Clinical Center (CC)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations