Completed PHASE2 INTERVENTIONAL 3-arm NCT01300208

To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythematosus and Subacute Cutaneous Lupus Erythematosus

A Phase 2, Pilot, Multicenter, Sequential, Ascending Dose Study to Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythematosus and Subacute Cutaneous Lupus Erythematosus

Sponsor: Amgen

Conditions Cutaneous Lupus Erythematosus

Interventions CC-11050 Placebo

Updated 10 times since 2017 Last updated: Jun 18, 2020 Started: Oct 1, 2010 Primary completion: Jan 1, 2013 Completion: Mar 1, 2013

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01300208, this PHASE2 trial focuses on Cutaneous Lupus Erythematosus and remains completed. Sponsored by Amgen, it has been updated 10 times since 2010, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

10 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Apr 2022 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Apr 2022 [monthly]

Completed PHASE2

▶ Show 5 earlier versions

Jul 2020 — Jan 2021 [monthly]

Completed PHASE2
Dec 2019 — Jul 2020 [monthly]

Completed PHASE2
Jun 2018 — Dec 2019 [monthly]

Completed PHASE2
Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Oct 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Amgen

Data source: Amgen

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Chicago, United States , Cleveland, United States , Dallas, United States , Duncansville, United States , Hershey, United States , Indianapolis, United States , Johnston, United States , Lake Charles, United States , Los Angeles, United States and 8 more locations