Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease
A One-year Open-label, Multicenter Trial to Assess Efficacy, Safety and Tolerability of Canakinumab (ACZ885) and the Efficacy and Safety of Childhood Vaccinations in Patients Aged 4 Years or Younger With Cryopyrin Associated Periodic Syndromes (CAPS)
Sponsor: Novartis Pharmaceuticals
Listed as NCT01302860, this PHASE3 trial focuses on Cryopyrin-associated Periodic Syndromes and Familial Cold Autoinflammatory Syndrome and remains completed. Sponsored by Novartis Pharmaceuticals, it has been updated 9 times since 2010, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.
Status Flow
Change History
9 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE3
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Sep 2024 — Sep 2025 [monthly]
Completed PHASE3
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE3
-
Jan 2023 — Jul 2024 [monthly]
Completed PHASE3
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Dec 2022 — Jan 2023 [monthly]
Completed PHASE3
▶ Show 4 earlier versions
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Jan 2021 — Dec 2022 [monthly]
Completed PHASE3
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Jun 2018 — Jan 2021 [monthly]
Completed PHASE3
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Feb 2017 — Jun 2018 [monthly]
Completed PHASE3
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Jan 2017 — Feb 2017 [monthly]
Completed PHASE3
First recorded
Nov 2010
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Novartis Pharmaceuticals
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Berlin, Germany , Brussels, Belgium , Dresden, Germany , Granada, Spain , Laken, Belgium , Lausanne, Switzerland , Le Kremlin-Bicêtre, France , London, United Kingdom , Sankt Augustin, Germany , Toronto, Canada and 2 more locations