deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT01305941

A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain Metastases

A Phase II Study Evaluating The Efficacy And Tolerability Of Everolimus (RAD001) In Combination With Trastuzumab And Vinorelbine In The Treatment Of Progressive HER2-Positive Breast Cancer Brain Metastases

Sponsor: Novartis Pharmaceuticals

Updated 11 times since 2017 Last updated: Dec 13, 2018 Started: Sep 30, 2011 Primary completion: Aug 31, 2016 Completion: Oct 16, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01305941, this PHASE2 trial focuses on HER-2 Positive Breast Cancer and remains completed. Sponsored by Novartis Pharmaceuticals, it has been updated 11 times since 2011, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshotRecruiting~Apr 2017 – ~Nov 2017 · 7 months · monthly snapshotActive Not Recruiting~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshotActive Not Recruiting~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshotCompleted~Aug 2018 – ~Jan 2019 · 5 months · monthly snapshotCompleted~Jan 2019 – ~Jan 2021 · 24 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  4. Jan 2019 — Jan 2021 [monthly]

    Completed PHASE2

  5. Aug 2018 — Jan 2019 [monthly]

    Completed PHASE2

Show 6 earlier versions
  1. Jul 2018 — Aug 2018 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE2

  3. Nov 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  4. Apr 2017 — Nov 2017 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Feb 2017 — Apr 2017 [monthly]

    Recruiting PHASE2

  6. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Sep 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
  • UNC Lineberger Comprehensive Cancer Center
Data source: UNC Lineberger Comprehensive Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .