deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT01313611

BRIEF Bendamustine and Rituximab In Elderly Follicular (BRIEF)

BRIEF: Bendamustine and Rituximab In Elderly Follicular: A Multicentric Phase II Study Evaluating the Benefit of a Short Induction Treatment by Bendamustine and Rituximab Followed by Maintenance Therapy With Rituximab In Elderly (≥ 60 Years Old) Patients With Untreated Follicular Lymphoma Patients, With an Intermediate or High FLIPI Score

Sponsor: The Lymphoma Academic Research Organisation

Updated 12 times since 2017 Last updated: Mar 6, 2018 Started: Feb 28, 2011 Primary completion: Oct 31, 2012 Completion: Dec 31, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Treament with rituximab during maintenance phase was stoped, according to DSMC recommendations, since 3 cases of deaths occured.

A PHASE2 clinical study on Follicular Lymphoma, this trial is terminated or withdrawn. The trial is conducted by The Lymphoma Academic Research Organisation and has accumulated 12 data snapshots since 2011. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshotTerminated~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshotTerminated~Oct 2017 – ~Mar 2018 · 5 months · monthly snapshotTerminated~Mar 2018 – ~May 2018 · 2 months · monthly snapshotTerminated~May 2018 – ~Jun 2018 · 31 days · monthly snapshotTerminated~Jun 2018 – ~Nov 2020 · 29 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 12 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE2

Show 7 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  2. Jun 2018 — Nov 2020 [monthly]

    Terminated PHASE2

  3. May 2018 — Jun 2018 [monthly]

    Terminated PHASE2

  4. Mar 2018 — May 2018 [monthly]

    Terminated PHASE2

  5. Oct 2017 — Mar 2018 [monthly]

    Terminated PHASE2

  6. Aug 2017 — Oct 2017 [monthly]

    Terminated PHASE2

  7. Jan 2017 — Aug 2017 [monthly]

    Terminated PHASE2

    First recorded

Feb 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • The Lymphoma Academic Research Organisation
Data source: The Lymphoma Academic Research Organisation

For direct contact, visit the study record on ClinicalTrials.gov .