Completed PHASE1 INTERVENTIONAL 2-arm NCT01321346

A Study Of Panobinostat In Children With Refractory Hematologic Malignancies

A Phase I Dose Finding Study Of Panobinostat In Children With Refractory Hematologic Malignancies

Sponsor: Novartis

Conditions Hodgkin's Disease Lymphoblastic Leukemia, Acute, Childhood Myelogenous Leukemia, Acute, Childhood Non-Hodgkin's Lymphoma

Interventions Cytarabine Panobinostat

Updated 7 times since 2017 Last updated: Nov 20, 2015 Started: Mar 31, 2011 Primary completion: Oct 31, 2015

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01321346, this PHASE1 trial focuses on Hodgkin's Disease and Lymphoblastic Leukemia, Acute, Childhood and remains completed. Sponsored by Novartis, it has been updated 7 times since 2011, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE1
Sep 2024 — Sep 2025 [monthly]

Completed PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1
Jun 2018 — Jan 2021 [monthly]

Completed PHASE1

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE1
Jan 2017 — Feb 2017 [monthly]

Completed PHASE1

First recorded

Mar 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Novartis
Therapeutic Advances in Childhood Leukemia Consortium

Data source: Therapeutic Advances in Childhood Leukemia Consortium

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ann Arbor, United States , Atlanta, United States , Boston, United States , Charlotte, United States , Chicago, United States , Cleveland, United States , Columbus, United States , Los Angeles, United States , Memphis, United States , Miami, United States and 9 more locations