Completed PHASE3 INTERVENTIONAL 2-arm NCT01358357

Bipolar Maintenance Study of Lurasidone Adjunctive to Lithium or Divalproex (PERSIST)

A Randomized, Double-blind, Placebo-controlled, Flexible-dose, Parallel-group Study of Lurasidone Adjunctive to Lithium or Divalproex for the Prevention of Recurrence in Subjects With Bipolar I Disorder

Sponsor: Sumitomo Pharma America, Inc.

Conditions Bipolar I Disorder

Interventions Lurasidone Placebo

Updated 8 times since 2017 Last updated: Jul 29, 2016 Started: Jun 30, 2011 Primary completion: Apr 30, 2015 Completion: Apr 30, 2015

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01358357, this PHASE3 trial focuses on Bipolar I Disorder and remains completed. Sponsored by Sumitomo Pharma America, Inc., it has been updated 8 times since 2011, reflecting limited change activity. Mental health research at this phase helps define safety and dosing parameters for future study.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Sep 2023 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Sep 2023 [monthly]

Completed PHASE3

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Jun 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Sumitomo Pharma America, Inc.

Data source: Sumitomo Pharma America, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aichi, Japan , Atlanta, United States , Belgrade, Serbia , Bradenton, United States , Brno, Czechia , Brno-Bohunice, Czechia , Budapest, Hungary , Buenos Aires, Argentina , Burgas, Bulgaria , Charleston, United States and 76 more locations