deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT01375699

Doxorubicin With or Without Sildenafil, With Analysis of Cardiac Markers

Randomized Open-label Phase 1b Study of Doxorubicin-based Chemotherapy Regimens, With and Without Sildenafil, With Exploratory Analysis of Intermediate Cardiac Markers

Sponsor: Virginia Commonwealth University

Updated 12 times since 2017 Last updated: Aug 22, 2019 Started: Aug 11, 2011 Primary completion: Aug 4, 2017 Completion: Jan 19, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Breast Cancer and Gastrointestinal Cancer, this trial is completed. The trial is conducted by Virginia Commonwealth University and has accumulated 12 data snapshots since 2011. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshotActive Not Recruiting~Apr 2017 – ~Nov 2017 · 7 months · monthly snapshotActive Not Recruiting~Nov 2017 – ~Feb 2018 · 3 months · monthly snapshotActive Not Recruiting~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshotCompleted~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshotCompleted~Nov 2018 – ~Aug 2019 · 9 months · monthly snapshotCompleted~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshotCompleted~Sep 2019 – ~Jan 2021 · 16 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Sep 2019 — Jan 2021 [monthly]

    Completed PHASE1

  5. Aug 2019 — Sep 2019 [monthly]

    Completed PHASE1

Show 7 earlier versions
  1. Nov 2018 — Aug 2019 [monthly]

    Completed PHASE1

  2. Jun 2018 — Nov 2018 [monthly]

    Completed PHASE1

  3. Feb 2018 — Jun 2018 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  4. Nov 2017 — Feb 2018 [monthly]

    Active Not Recruiting PHASE1

  5. Apr 2017 — Nov 2017 [monthly]

    Active Not Recruiting PHASE1

  6. Feb 2017 — Apr 2017 [monthly]

    Active Not Recruiting PHASE1

  7. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Aug 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Virginia Commonwealth University
Data source: Virginia Commonwealth University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations