deltatrials
Completed PHASE2 NCT01375751

Reduction of Low-Density Lipoprotein Cholesterol (LDL-C) With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study

A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate Tolerability and Efficacy of AMG 145 on LDL-C in Subject With Heterozygous Familial Hypercholesterolemia

Sponsor: Amgen

Updated 11 times since 2017 Last updated: Nov 10, 2022 Started: Aug 2, 2011 Primary completion: May 16, 2012 Completion: May 16, 2012

Listed as NCT01375751, this PHASE2 trial focuses on Hypercholesterolemia, Familial and remains completed. Sponsored by Amgen, it has been updated 11 times since 2011, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Dec 2022 — Jul 2024 [monthly]

    Completed PHASE2

  4. Feb 2021 — Dec 2022 [monthly]

    Completed PHASE2

  5. Jan 2021 — Feb 2021 [monthly]

    Completed PHASE2

Show 6 earlier versions
  1. Dec 2018 — Jan 2021 [monthly]

    Completed PHASE2

  2. Oct 2018 — Dec 2018 [monthly]

    Completed PHASE2

  3. Sep 2018 — Oct 2018 [monthly]

    Completed PHASE2

  4. Jun 2018 — Sep 2018 [monthly]

    Completed PHASE2

  5. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE2

  6. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Aug 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Amgen
Data source: Amgen

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.