deltatrials
Completed PHASE1 INTERVENTIONAL NCT01386489

Immune Responses to Two Experimental HIV Vaccines in Healthy Adults

VRC 016: A Phase 1b Open-Label, Randomized Clinical Trial to Evaluate Early Innate and Adaptive Immune Responses to the Investigational HIV-1 Vaccines: VRC-HIVADV014-00-VP and VRC-HIVDNA016-00-VP in Ad5 Seronegative Healthy Adults

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Conditions Adaptive Immunity HIV Negative Innate Immunity
Interventions VRC-HIVADV014-00-VP VRC-HIVDNA016-00-VP
Updated 23 times since 2017 Last updated: Dec 13, 2019 Started: Jun 17, 2011 Primary completion: Mar 9, 2014 Completion: Mar 19, 2014
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Adaptive Immunity and HIV Negative and is currently completed. National Institute of Allergy and Infectious Diseases (NIAID) leads this study, which shows 23 recorded versions since 2011 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Jan 2021 · 12 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

23 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Jan 2020 — Jan 2021 [monthly]

    Completed PHASE1

  5. Dec 2019 — Jan 2020 [monthly]

    Completed PHASE1

▶ Show 18 earlier versions

  1. Oct 2019 — Dec 2019 [monthly]

    Completed PHASE1

  2. Sep 2019 — Oct 2019 [monthly]

    Completed PHASE1

  3. Aug 2019 — Sep 2019 [monthly]

    Completed PHASE1

  4. Jul 2019 — Aug 2019 [monthly]

    Completed PHASE1

  5. Jun 2019 — Jul 2019 [monthly]

    Completed PHASE1

  6. Apr 2019 — Jun 2019 [monthly]

    Completed PHASE1

  7. Mar 2019 — Apr 2019 [monthly]

    Completed PHASE1

  8. Feb 2019 — Mar 2019 [monthly]

    Completed PHASE1

  9. Jan 2019 — Feb 2019 [monthly]

    Completed PHASE1

  10. Dec 2018 — Jan 2019 [monthly]

    Completed PHASE1

  11. Nov 2018 — Dec 2018 [monthly]

    Completed PHASE1

  12. Oct 2018 — Nov 2018 [monthly]

    Completed PHASE1

  13. Sep 2018 — Oct 2018 [monthly]

    Completed PHASE1

  14. Aug 2018 — Sep 2018 [monthly]

    Completed PHASE1

  15. Jul 2018 — Aug 2018 [monthly]

    Completed PHASE1

  16. Jun 2018 — Jul 2018 [monthly]

    Completed PHASE1

  17. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE1

  18. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE1

    First recorded

Jun 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Allergy and Infectious Diseases (NIAID)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations