Completed PHASE1/PHASE2 INTERVENTIONAL 4-arm NCT01394939

Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma

A Phase 1/2a Dose-escalation Study of JX 594 Administered by Multiple Intravenous (IV) Infusions Alone and in Combination With Irinotecan in Patients With Metastatic, Refractory Colorectal Carcinoma.

Sponsor: Jennerex Biotherapeutics

Conditions CRC Colorectal Carcinoma

Interventions Irinotecan JX-594

Updated 7 times since 2017 Last updated: Dec 11, 2020 Started: Jan 31, 2012 Primary completion: Jun 30, 2015 Completion: Oct 31, 2015

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01394939, this PHASE1/PHASE2 trial focuses on CRC and Colorectal Carcinoma and remains completed. Sponsored by Jennerex Biotherapeutics, it has been updated 7 times since 2012, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE1/PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1/PHASE2

Phase: PHASE1_PHASE2 → PHASE1/PHASE2
Feb 2021 — Jul 2024 [monthly]

Completed PHASE1_PHASE2
Jan 2021 — Feb 2021 [monthly]

Completed PHASE1_PHASE2
Jun 2018 — Jan 2021 [monthly]

Completed PHASE1_PHASE2

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE1_PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE1_PHASE2

First recorded

Jan 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Jennerex Biotherapeutics
Transgene

Data source: SillaJen, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Billings, United States , Canton, United States , Chapel Hill, United States , Columbus, United States , Hamilton, Canada , La Jolla, United States , Ottawa, Canada , Paris, France , Scottsdale, United States , Strasbourg, France and 1 more location