Completed PHASE4 INTERVENTIONAL 3-arm NCT01395069

Prophylactic Nepafenac and Ketorolac Versus Placebo in Patients Undergoing Cataract Surgery (PNK)

Randomized Clinical Trial Comparing Prophylactic Nepafenac 0.1% and Ketorolac 0.5% Versus Placebo in Preventing Postoperative Macular Edema After Uncomplicated Phacoemulsification Cataract Extraction (PNK)

Sponsor: Queen's University

Conditions Macular Edema

Interventions Ketorolac 0.5% Nepafenac 0.1% Placebo (sterile saline drops)

Updated 7 times since 2017 Last updated: Jan 12, 2016 Started: Feb 28, 2010 Primary completion: May 31, 2011 Completion: May 31, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Macular Edema and is currently completed. Queen's University leads this study, which shows 7 recorded versions since 2010 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

7 versions recorded

Jun 2025 — Present [monthly]

Completed PHASE4
Apr 2025 — Jun 2025 [monthly]

Completed PHASE4
Sep 2024 — Apr 2025 [monthly]

Completed PHASE4
Jul 2024 — Sep 2024 [monthly]

Completed PHASE4
Jan 2021 — Jul 2024 [monthly]

Completed PHASE4

▶ Show 2 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE4
Jan 2017 — Jun 2018 [monthly]

Completed PHASE4

First recorded

Feb 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Queen's University

Data source: Queen's University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Kingston, Canada