deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT01414426

Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck Lesions

Randomized Placebo- Controlled Pilot Study of ZD6474 as a Chemopreventive Agent for Premalignant Lesions of the Head and Neck

Sponsor: National Cancer Institute (NCI)

Updated 11 times since 2017 Last updated: Jan 8, 2021 Started: Jan 31, 2012 Primary completion: Jan 1, 2019 Completion: Jun 1, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Lip and Oral Cavity Squamous Cell Carcinoma and Oral Cavity Verrucous Carcinoma, this trial is completed. The trial is conducted by National Cancer Institute (NCI) and has accumulated 11 data snapshots since 2012. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Mar 2018 · 13 months · monthly snapshotRecruiting~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Mar 2020 · 21 months · monthly snapshotActive Not Recruiting~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshotUnknown Status~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotUnknown Status~Feb 2021 – ~Dec 2022 · 22 months · monthly snapshotCompleted~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotCompleted~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

  5. Feb 2021 — Dec 2022 [monthly]

    Completed PHASE2

    Status: Unknown StatusCompleted

Show 6 earlier versions
  1. Jan 2021 — Feb 2021 [monthly]

    Unknown Status PHASE2

  2. Mar 2020 — Jan 2021 [monthly]

    Unknown Status PHASE2

    Status: Active Not RecruitingUnknown Status

  3. Jun 2018 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

  4. Mar 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Feb 2017 — Mar 2018 [monthly]

    Recruiting PHASE2

  6. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Jan 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • University of Chicago
Data source: University of Chicago

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations